Saturday, January 18, 2014

What is HIV/Aids?

Busting HIV Transmission Myths

 
  • What Is HIV?

    Human immunodeficiency virus (HIV) is a virus that attacks the immune system. HIV can cause acquired immune deficiency syndrome (AIDS), a disease that severely weakens immunity, and can be fatal.
    One person passes HIV to another under certain circumstances. Understanding the facts rather than buying into lingering myths abouttransmission can prevent misinformation—and HIV—from spreading.

    Transmission Through Body Fluids

    HIV is transmitted through certain body fluids that are capable of containing high concentrations of HIV antibodies, such as blood, semen, vaginal and rectal secretions, and breast milk.
    HIV is transmitted when fluids from an infected person (HIV positive) pass through the mucous membranes, cuts, open sores, or tears in the skin of a non-infected person (HIV negative).
    Other bodily fluids, such as tears and saliva, have very small quantities of HIV antibodies and carry only a remote risk of infection, according to theCenters for Disease Control and Prevention (CDC). Amniotic and spinal cord fluids can also contain the HIV virus, and may be a risk to health care personnel who are exposed to them.

    The Anatomy of Transmission

    Vaginal sex is one mode of HIV transmission. In rare cases, oral sex with someone who is infected can spread HIV. However, anal sex presents the highest risk of transmission among sexual activity. Bleeding is more likely during anal sex due to the fragile tissues that line the anus. This allows the virus to enter the body more easily.
    HIV can also be spread from mother to child in utero and through breastfeeding. Any circumstances in which you are exposed to the blood of someone who is HIV positive can be a risk factor. This includes sharing needles for IV drug use or getting a tattoo with contaminated instruments. Safety regulations generally prevent blood transfusion-related infection.

    Blood Banks Are Safe

    The risk of being infected with HIV from a blood transfusion is now extremely rare in the United States. The Public Health Service started testing all donated blood for HIV in 1985, after medical personnel realized that donated blood could be a source of HIV infection. Tests that are more sophisticated were put into place in the 1990s to further ensure the safety of donated blood, according to the CDC. Blood donations that testpositive for HIV are safely discarded and do not enter the U.S. blood supply.

    Casual Contact and Kissing

    Many people are afraid that casual contact or kissing someone who has HIV can spread the infection. The virus doesn’t live on the skin and can’t live very long outside the body. Therefore casual contact, such as holding hands, hugging, or sitting next to someone who is HIV positive doesn’t transmit HIV. 
    According to UK-based HIV/AIDS organization AVERT, closed-mouth kissing isn’t a threat either. Open-mouthed kissing can be a risk factor when blood is involved, such as from bleeding gums or mouth sores. Saliva may contain small amounts of viral load, but not enough to transmit the virus.

    Transmission Myths: Biting, Scratching, and Spitting

    Scratching and spitting aren’t transmission methods for HIV. A scratch doesn’t lead to an exchange of bodily fluids. However, you can protect yourself with gloves to prevent the accidental exposure to infected blood when drawing blood from someone who is infected with HIV.
    A bite that doesn’t break the skin can’t transmit infection either. However, a bite that opens the skin and causes bleeding can. According to theCDC, this has happened in a small number of cases that involved a blood-to-blood transfer between the biter and the person bit.

    Protect Yourself: Safe Sex

    You can protect yourself from HIV infection by practicing safe sex. Safe sex means using a new condom every time you have vaginal, oral, or anal sex. Remember to use water-based lubricants with condoms. Oil-based products can break down the latex, increasing the risk of leaks.
    Safe sex also involves keeping open lines of communication with your partner. Discuss the risks associated with unprotected sex, and reveal your HIV status to your partner. It’s especially important to use condoms if one of you is HIV positive. An HIV-negative partner should be tested for the virus periodically.

    Protect Yourself: Clean Needles

    Contaminated drug needles can be a source of infection because the first prick of the needle brings a drop of blood to the surface. If the needle contains HIV antibodies, you’re at high-risk for infection. Many communities offer needle exchange programs that provide clean needles to reduce the spread of HIV. Make use of this resource as needed, and consider asking for help to get off drugs.

    Education Banishes Myths and Stigmas

    When HIV first emerged, being HIV positive was a sure death sentence with a huge stigma attached to it. Researchers have studied transmission extensively and developed treatment that allows many people who are infected to live long, productive lives.
    Today, the stigma isn’t as great because more people understand the way HIV is spread. But let’s not stop there. Continued education is the key to banishing the myths and the spread of HIV.

Portable Device Tests for HIV With a Single Drop of Blood

HealthlineNews

Portable Device Tests for HIV With a Single Drop of Blood

    
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Advances in T-cell analysis give hope to HIV and ovarian cancer patients.
Portable HIV Test
A new technology that provides a complete HIV test and T-cell count in less than 20 minutes could revolutionize how the disease is diagnosed in remote parts of the world. 
The study detailing the device, published today in Science Translational Medicine, comes just 24 hours after the release of a report showing that antiretroviral therapy (ART) has saved 2.8 million years of life in South Africa since 2004. Using what the authors say are conservative estimates, computer simulations predicted that an additional 15.1 million years of life will be be saved by 2030 among those receiving the costly treatment in the sub-Saharan nation.
That report, published in the Journal of Infectious Diseases, didn't take into account the advantages of a device like the one described in today's study. A handheld version of the tool is expected to be developed within the next few years, making it easier to deploy to remote regions. With just a single drop of blood, the device can provide a total CD4-CD8 profile, which measures the types of white blood cells present in the body and offers a more complete measure of immune system function.
The test can quickly determine whether a person is eligible to begin the lifesaving ARTtreatment, even if they are not yet aware that they have the disease. The World Health Organization (WHO) recommends beginning ART when a person's T-cell count falls below 500. T-cells, including CD4 and CD8 cells, are helper cells that boost the immune system. 

How Does It Work?

Currently small enough to place on a table, the HIV testing device uses electricity to count and classify T-cells. Essentially, it's a lab on a microchip. Its developers hope to make the device widely available for clinical use within the next three years.
“Other technologies use optics that are generally more costly, fragile, and bulky,” Nicholas Watkins, one of the study's authors, told Healthline. 
Watkins, a research scientist at Nabsys Inc. in Providence, R.I., said that the device is sturdier and less expensive than existing technologies. The traditional method is like “a portable CD player versus an mp3 player that is solid state with all electrical components,” he said.
Dr. Michael April, lead author of the ART study in South Africa, told Healthline that both developments pack a one-two punch for quashing HIV in under-served areas.
Having a portable tool available to rapidly assess HIV could allow doctors in places like South Africa to better monitor the progression of the disease. This could lead to quicker deployment of second-line treatment. 
“Access to second-line ART has a huge impact if it's universally available,” said April, of the San Antonio Uniformed Services Health Education Consortium.
According to 2012 UNAIDS estimates, about 18 percent of people in South Africa ages 15 to 49 have HIV. About one-third of those infected with HIV are eligible for ART but don't receive it. April said that the scope of the problem in South Africa adds to the staggering number oflife-years saved by ART.
“We're finally starting to have a lot of success,” April said of battling HIV worldwide. “It's finally starting to look like we're stemming the tide a little bit and really starting to make some great progress.”
Rashid Bashir, an author of the study on the testing device, said that the technology could also be useful in remote or limited-resource areas in the U.S. Bashir, a professor at the University of Illinois, said that it could be used to measure all different cell types, and could have many other applications for diagnosing and monitoring disease. 

A New Way to Calculate Cancer Survival

Also today, a paper published in Science Translational Medicine reports that a new device can digitally count a type of T-cell that can help predict how long ovarian cancer patients will live: the tumor-infiltrating lymphocyte (TIL).
Although a higher count of TILs is thought to be associated with longer survival, they are also found in metastasized tumors, which are removed during surgery. This creates a paradox, according to Franck Pagès, a French researcher who wrote an accompanying article in the medical journal.
Jason Bielas, a cancer researcher at the University of Washington, says that his device scans a T-cell's DNA, which is like a “barcode,” revealing a wealth of information. He said that it will be useful as personalized medicine—treatments specially tailored to a patient—becomes more common.
Although not portable like Watkins' device, he hopes to see it used one day in clinical settings.

Porn actor tests positive for HIV,


HealthlineNews

U.S. Porn Industry Under Third Moratorium This Year

    
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Another porn actor tests positive for HIV, halting adult film production in California.
Porn Industry Moratorium
The Free Speech Coalition (FSC), an adult filmindustry trade group, announced that another performer has tested positive for HIV during a mandatory two-week Performer Availability Screening Services-certified testing for sexually transmitted infections.
The actor is now working with doctors to determine whether the larger talent pool was affected. Meanwhile, the U.S. pornography industry remains under moratorium.
The FSC also said all actors who had been in first-hand contact with the infected person have been notified and are undergoing re-testing. The name of the latest performer to test positive was not released under federal health privacy laws.
“We want to remind those who would point fingers—either at the performer or his or her work—is that HIV is a virus, not a moral issue,” FSC representatives said in a statement. “It affects all people, and all populations, and occupations; all of them deserve compassion.”

Moratoriums Spark Condom Debate

This is the U.S. pornography industry's third moratorium this year following an actor testing positive for the HIV virus. 
In September, actors Cameron Bay and her real-life partner Rod Daily tested positive for the virus and spoke out about conditions inside the pornography industry. Bay told the Huffington Post that there were numerous chances to use a condom onscreen, but she declined, trusting the HIV screening systems in place.
FSC said Bay’s and Daily’s infections were determined to have occurred offsite.
In January, Los Angeles Mayor Antonio Villaraigosa signed a law requiring condoms in all pornography filmed within city limits. Since then, pornography production in the area has dropped by 95 percent, according to the Los Angeles Times.
One of the filming sites at the center of the previous moratorium was Kink.com, a San Francisco-based porn production facility.
The FSC said that despite rumors, the newly-infected actor did not work with Bay, Daily, or at the Kink site.